ARG46472

anti-SHISA3 antibody

anti-SHISA3 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes SHISA3
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SHISA3
抗原物种 Human
抗原 A 15 amino acid synthetic peptide within the last 50 amino acids of human SHISA3.
偶联标记 Un-conjugated
別名 shisa homolog 3 (Xenopus laevis); SHISA3; hShisa3; Protein shisa-3 homolog

应用说明

应用建议
应用 推荐稀释比
IHC-PAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 28 kDa

属性

形式 Liquid
纯化 Affinity chromatography purified
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -522°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 152573 Human SHISA3

GeneID: 330096 Mouse SHISA3

Swiss-port # A0PJX4 Human Protein shisa-3 homolog

Swiss-port # Q3UPR0 Mouse Protein shisa-3 homolog

基因名称 SHISA3
全名 shisa homolog 3 (Xenopus laevis)
背景介绍 This gene encodes a single-transmembrane protein which is one of nine members of a family of transmembrane adaptors that modulate both WNT and FGF signaling by blocking the maturation and transport of their receptors to the cell surface. Members of this family contain an N-terminal cysteine-rich domain with a distinct cysteine pattern, a single transmembrane domain, and a C-terminal proline-rich, low complexity region. The encoded protein acts as a tumor suppressor by accelerating beta-catenin degradation. [provided by RefSeq, Jul 2017]
生物功能 Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. [UniProt]
细胞定位 Endoplasmic reticulum membrane. [UniProt]
预测分子量 26 kDa