ARG59090

anti-SGCA / alpha Sarcoglycan antibody

anti-SGCA / alpha Sarcoglycan antibody for ICC/IF,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes SGCA / alpha Sarcoglycan
反应物种 Hu, Ms, Rat
应用 ICC/IF, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SGCA / alpha Sarcoglycan
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 60-290 of Human SGCA / alpha Sarcoglycan (NP_000014.1).
偶联标记 Un-conjugated
別名 adhalin; Adhalin; 50 kDa dystrophin-associated glycoprotein; Alpha-sarcoglycan; 50-DAG; Alpha-SG; SCARMD1; DMDA2; 50DAG; Dystroglycan-2; A2; DAG2; ADL; LGMD2D

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 A549
实际分子量 43kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20391 Mouse SGCA

GeneID: 6442 Human SGCA

Swiss-port # P82350 Mouse Alpha-sarcoglycan

Swiss-port # Q16586 Human Alpha-sarcoglycan

基因名称 SGCA
全名 sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
背景介绍 This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
生物功能 Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. [UniProt]
细胞定位 Cell membrane, sarcolemma; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. [UniProt]
预测分子量 43 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG59090 anti-SGCA / alpha Sarcoglycan antibody WB image

    Western blot: 25 µg of A549 cell lysate stained with ARG59090 anti-SGCA / alpha Sarcoglycan antibody at 1:3000 dilution.