ARG59105
anti-SFTPB / Prosurfactant Protein B antibody
anti-SFTPB / Prosurfactant Protein B antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SFTPB / Prosurfactant Protein B |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SFTPB / Prosurfactant Protein B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to a sequence of Human SFTPB / Prosurfactant Protein B. (QCLAERYSVILLDTLLGRMLPQLVCRLVLR). |
| 偶联标记 | Un-conjugated |
| 別名 | SP-B; 18 kDa pulmonary-surfactant protein; SFTP3; Phe; Pulmonary surfactant-associated proteolipid SPL; PSP-B; Pulmonary surfactant-associated protein B; 6 kDa protein; SMDP1; SFTB3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P07988 Human Pulmonary surfactant-associated protein B |
|---|---|
| 基因名称 | SFTPB |
| 全名 | surfactant protein B |
| 背景介绍 | This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010] |
| 生物功能 | Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. [UniProt] |
| 细胞定位 | Secreted, extracellular space, surface film. [UniProt] |
| 预测分子量 | 42 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59105 anti-SFTPB / Prosurfactant Protein B antibody WB image
Western blot: 50 µg of samples under reducing conditions. MCF-7, COLO-320 and HepG2 cell lysates stained with ARG59105 anti-SFTPB / Prosurfactant Protein B antibody at 0.5 µg/ml, overnight at 4°C.
