概述

产品描述	Rabbit Polyclonal antibody recognizes SFRP4
反应物种	Hu, Ms, Rat
应用	FACS, ICC/IF, IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	SFRP4
抗原物种	Human
抗原	Synthetic peptide derived from Human SFRP4.
偶联标记	Un-conjugated
別名	Frizzled protein, human endometrium; FRP-4; FRPHE; Secreted frizzled-related protein 4; FrpHE; sFRP-4

应用说明

应用建议	应用 推荐稀释比 FACS 1:50 ICC/IF 1:50 - 1:200 IHC-P 1:50 - 1:200 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	293T
实际分子量	~ 51 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 20379 Mouse SFRP4 GeneID: 6424 Human SFRP4 GeneID: 89803 Rat SFRP4 Swiss-port # Q6FHJ7 Human Secreted frizzled-related protein 4 Swiss-port # Q9JLS4 Rat Secreted frizzled-related protein 4 Swiss-port # Q9Z1N6 Mouse Secreted frizzled-related sequence protein 4 More
基因名称	SFRP4
全名	secreted frizzled-related protein 4
背景介绍	Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq, Jul 2008]
生物功能	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927). [UniProt]
细胞定位	Secreted. Note=Cytoplasmic in ovarian tumor cells. [UniProt]
预测分子量	40 kDa

检测图片 (1) Click the Picture to Zoom In