ARG56891
anti-SERPINF1 / PEDF antibody
anti-SERPINF1 / PEDF antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SERPINF1 / PEDF |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SERPINF1 / PEDF |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-200 of Human SERPINF1 / PEDF (NP_002606.3). |
| 偶联标记 | Un-conjugated |
| 別名 | OI12; Pigment epithelium-derived factor; Cell proliferation-inducing gene 35 protein; Serpin F1; EPC-1; PEDF; PIG35; OI6 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse kidney and A375 | ||||
| 实际分子量 | 53 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SERPINF1 |
| 全名 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| 背景介绍 | The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.[provided by RefSeq, Mar 2011] |
| 生物功能 | Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. [UniProt] |
| 细胞定位 | Secreted. Melanosome. Note=Enriched in stage I melanosomes. [UniProt] |
| 预测分子量 | 46 kDa |
| 翻译后修饰 | The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity. N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG56891 anti-SERPINF1 / PEDF antibody WB image
Western blot: 25 µg of Mouse kidney and A375 cell lysates stained with ARG56891 anti-SERPINF1 / PEDF antibody at 1:1000 dilution.
