ARG58658

anti-SERPINB1 antibody

anti-SERPINB1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes SERPINB1
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 SERPINB1
抗原物种 Human
抗原 Recombinant fusion protein corresponding to aa. 100-379 of Human SERPINB1 (NP_109591.1).
偶联标记 Un-conjugated
別名 EI; LEI; ELANH2; Monocyte/neutrophil elastase inhibitor; Leukocyte elastase inhibitor; M/NEI; Serpin B1; MNEI; PI-2; PI2; Peptidase inhibitor 2; HEL57

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 MCF7
实际分子量 43 kDa

属性

形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 1992 Human SERPINB1

Swiss-port # P30740 Human Leukocyte elastase inhibitor

基因名称 SERPINB1
全名 serpin peptidase inhibitor, clade B (ovalbumin), member 1
背景介绍 The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
生物功能 Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H. [UniProt]
细胞定位 Cytoplasm, Cytoplasmic granule. [UniProt]
预测分子量 43 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG58658 anti-SERPINB1 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG58658 anti-SERPINB1 antibody.

  • ARG58658 anti-SERPINB1 antibody WB image

    Western blot: 25 µg of MCF7 cell lysate stained with ARG58658 anti-SERPINB1 antibody at 1:1000 dilution.