ARG45641
anti-SELT antibody
anti-SELT antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SELT |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SELT |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SELT. |
| 偶联标记 | Un-conjugated |
| 別名 | SELENOT; Selenoprotein T; SELT; Thioredoxin Reductase-Like Selenoprotein T; Thioredoxin Reductase-Like Enzyme; EC 1.8.1.9; SelT |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 22 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SELENOT |
| 全名 | Selenoprotein T |
| 背景介绍 | This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif found in several redox active proteins. Studies in mice indicate a crucial role for this gene in the protection of dopaminergic neurons against oxidative stress in Parkinson's disease, and in the control of glucose homeostasis in pancreatic beta-cells. Pseudogenes of this locus have been identified on chromosomes 9 and 5. [provided by RefSeq, Sep 2017] |
| 生物功能 | Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity). Protects dopaminergic neurons against oxidative stress and cell death. [UniProt] |
| 细胞定位 | Endoplasmic reticulum; Membrane. [UniProt] |
| 预测分子量 | 22 kDa |
检测图片 (7) Click the Picture to Zoom In
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ARG45641 anti-SELT antibody IHC-P image
Immunohistochemistry: Human lung adenocarcinoma stained with ARG45641 anti-SELT antibody at 2 μg/ml dilution.
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ARG45641 anti-SELT antibody WB image
Western blot: RT4 stained with ARG45641 anti-SELT antibody at 0.5 μg/ml dilution.
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ARG45641 anti-SELT antibody FACS image
Flow Cytometry: HL-60 stained with ARG45641 anti-SELT antibody at 1 µg/10^6 cells dilution.
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ARG45641 anti-SELT antibody IHC-P image
Immunohistochemistry: Rat kidney stained with ARG45641 anti-SELT antibody at 2 μg/ml dilution.
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ARG45641 anti-SELT antibody WB image
Western blot: Rat pancreas stained with ARG45641 anti-SELT antibody at 0.5 μg/ml dilution.
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ARG45641 anti-SELT antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45641 anti-SELT antibody at 2 μg/ml dilution.
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ARG45641 anti-SELT antibody WB image
Western blot: Mouse pancreas stained with ARG45641 anti-SELT antibody at 0.5 μg/ml dilution.
