ARG44349
anti-SEC14L2 / TAP antibody
anti-SEC14L2 / TAP antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SEC14L2 / TAP |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SEC14L2 / TAP |
| 抗原物种 | Human |
| 抗原 | Human SEC14L2 / TAP recombinant fusion protein (a.a. sequence: 60-270). |
| 偶联标记 | Un-conjugated |
| 別名 | SEC14L2; SEC14 Like Lipid Binding 2; TAP; SPF; Supernatant Protein Factor; KIAA1186; KIAA1658; C22orf6; TAP1; Alpha-Tocopherol-Associated Protein; Tocopherol-Associated Protein 1; Squalene Transfer Protein; SEC14-Like Protein 2; SEC14 (S. Cerevisiae)-Like 2; SEC14-Like 2 (S. Cerevisiae); SEC14-Like Lipid Binding 2; HTAP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS, 0.01% Thimerosal and 50% Glycerol. |
| 抗菌剂 | 0.01% Thimerosal |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SEC14L2 |
| 全名 | SEC14 Like Lipid Binding 2 |
| 背景介绍 | This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
| 生物功能 | Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. |
| 细胞定位 | Cytoplasm, Nucleus |
| 预测分子量 | 46 kDa |
检测图片 (6) Click the Picture to Zoom In
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ARG44349 anti-SEC14L2 / TAP antibody IHC-P image
Immunohistochemistry: Human esophageal cancer stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:200 dilution.
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ARG44349 anti-SEC14L2 / TAP antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:100 dilution.
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ARG44349 anti-SEC14L2 / TAP antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:200 dilution.
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ARG44349 anti-SEC14L2 / TAP antibody WB image
Western blot: Rat Liver stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:1000 dilution.
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ARG44349 anti-SEC14L2 / TAP antibody IHC-P image
Immunohistochemistry: Mouse pancreas stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:200 dilution.
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ARG44349 anti-SEC14L2 / TAP antibody WB image
Western blot: Mouse Liver and Mouse Lung stained with ARG44349 anti-SEC14L2 / TAP antibody at 1:1000 dilution.
