ARG64911
anti-SCARB2 / LIMP2 antibody
anti-SCARB2 / LIMP2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes SCARB2 / LIMP2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SCARB2 / LIMP2 |
| 抗原物种 | Human |
| 抗原 | C-NKANIQFGDNGTTIS |
| 偶联标记 | Un-conjugated |
| Protein Full name | Lysosome membrane protein 2 |
| 別名 | EPM4; LIMP-2; CD36L2; LIMPII; CD antigen CD36; LGP85; AMRF; LIMP II; HLGP85; Lysosome membrane protein 2; 85 kDa lysosomal membrane sialoglycoprotein; Lysosome membrane protein II; CD36 antigen-like 2; Scavenger receptor class B member 2; SR-BII |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Human cerebral cortex | ||||||
| 实际分子量 | ~ 80 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SCARB2 |
| 全名 | scavenger receptor class B member 2 |
| 背景介绍 | The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 54 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG64911 anti-SCARB2 / LIMP2 antibody IHC image
Immunohistochemistry: Paraffin-embedded Human cerebral cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64911 anti-SCARB2 / LIMP2 antibody at 3.8 µg/ml dilution, followed by AP-staining.
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ARG64911 anti-SCARB2 / LIMP2 antibody WB image
Western blot: 35 µg of Human cerebral cortex lysate stained with ARG64911 anti-SCARB2 / LIMP2 antibody at 0.1 µg/ml dilution and incubated at RT for 1 hour.
