ARG43455
anti-SCARA5 antibody
anti-SCARA5 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SCARA5 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Bov, Chk |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SCARA5 |
| 抗原物种 | Human |
| 抗原 | A 17-amino acid synthetic peptide within aa. 350 - 400 of Human SCARA5. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Scavenger receptor class A member 5 |
| 別名 | Tesr; NET33; Scavenger receptor class A member 5; Scavenger receptor hlg |
应用说明
| 预测反应性说明 | Based on sequence homology analysis: Bovine (100%), Mouse (88%), Chicken: (86%), Rat (80%) | ||||||
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| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human Liver Tissue Lysate, HepG2 | ||||||
| 实际分子量 | ~ 52 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZMJ2 Human Scavenger receptor class A member 5 |
|---|---|
| 基因名称 | SCARA5 |
| 全名 | scavenger receptor class A member 5 |
| 背景介绍 | SCARA5 (Scavenger Receptor Class A Member 5) is a Protein Coding gene. Diseases associated with SCARA5 include Prostate Leiomyosarcoma and Prostate Stromal Sarcoma. Among its related pathways are Binding and Uptake of Ligands by Scavenger Receptors and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and ferritin receptor activity. An important paralog of this gene is MSR1. [GeneCards] |
| 生物功能 | Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). |
| 细胞定位 | Cell membrane, Membrane |
| 预测分子量 | 54 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (3) Click the Picture to Zoom In
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ARG43455 anti-SCARA5 antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG43455 anti-SCARA5 antibody at 20 µg/ml dilution.
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ARG43455 anti-SCARA5 antibody WB image
Western blot: Human Liver tissue lysate stained with ARG43455 anti-SCARA5 antibody at 1 µg/ml dilution.
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ARG43455 anti-SCARA5 antibody ICC/IF image
Immunocytochemistry: HepG2 cells stained with ARG43455 anti-SCARA5 antibody at 2.5 µg/ml dilution.
