ARG45920
anti-SCAP antibody
anti-SCAP antibody for Western blot,Flow cytometry and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SCAP |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SCAP |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human SCAP. |
| 偶联标记 | Un-conjugated |
| 別名 | SREBF Chaperone; SCAP; KIAA0199; PSEC0227; Sterol regulatory element-binding protein cleavage-activating protein; SCAP; SREBP cleavage-activating protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 140 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SCAP |
| 全名 | SREBF Chaperone |
| 背景介绍 | This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| 生物功能 | Escort protein required for cholesterol as well as lipid homeostasis (By similarity). Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle; Endoplasmic reticulum; Golgi apparatus; Membrane. [UniProt] |
| 预测分子量 | 140 kDa |
| 翻译后修饰 | Glycoprotein; Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45920 anti-SCAP antibody WB image
Western blot: 293T stained with ARG45920 anti-SCAP antibody at 0.5 μg/ml dilution.
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ARG45920 anti-SCAP antibody FACS image
Flow Cytometry: 293T stained with ARG45920 anti-SCAP antibody at 1 µg/10^6 cells dilution.
