ARG44927
anti-SCAMP5 antibody
anti-SCAMP5 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody recognizes SCAMP5 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | SCAMP5 |
| 抗原物种 | Human |
| 抗原表位 | LPKFIPLKPC FYQDFEADIP |
| 偶联标记 | Un-conjugated |
| 別名 | SCAMP5; Secretory Carrier Membrane Protein 5; Secretory Carrier-Associated Membrane Protein 5; MGC24969; HSCAMP5 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8TAC9 Human Secretory carrier-associated membrane protein 5 Swiss-port # Q9JKD3 Mouse Secretory carrier-associated membrane protein 5 |
|---|---|
| 基因名称 | SCAMP5 |
| 全名 | Secretory Carrier Membrane Protein 5 |
| 背景介绍 | Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway. [UniProt] |
| 细胞定位 | Cell membrane, Cytoplasmic vesicle, Endosome, Golgi apparatus, Membrane, Synapse. [UniProt] |
| 预测分子量 | 26 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG44927 anti-SCAMP5 antibody IHC-P image
Immunohistochemistry: Human testis stained with ARG44927 anti-SCAMP5 antibody at 5 µg/mL dilution.
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ARG44927 anti-SCAMP5 antibody WB image
Western blot: Mouse brain stained with ARG44927 anti-SCAMP5 antibody at 1 µg/mL dilution.
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ARG44927 anti-SCAMP5 antibody IP image
Immunoprecipitation: Mouse brain lysate immunoprecipitated with 2.5 µg of ARG44927 anti-SCAMP5 antibody.
