ARG57006
anti-SBDS antibody [1E8]
anti-SBDS antibody [1E8] for Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [1E8] recognizes SBDS |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1E8 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | SBDS |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-250 of Human SBDS. |
| 偶联标记 | Un-conjugated |
| 別名 | Ribosome maturation protein SBDS; Shwachman-Bodian-Diamond syndrome protein; SWDS; CGI-97; SDS |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SBDS |
| 全名 | Shwachman-Bodian-Diamond syndrome |
| 背景介绍 | This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jul 2008] |
| 生物功能 | Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation. [UniProt] |
| 预测分子量 | 29 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG57006 anti-SBDS antibody [1E8] WB image
Western blot: 40 µg of 1) 293T cell lysate, 2) HeLa cell lysate stained with ARG57006 anti-SBDS antibody [1E8] at 1:3000.
