ARG57078
anti-S100A11 antibody [20D11]
anti-S100A11 antibody [20D11] for Flow cytometry,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [20D11] recognizes S100A11 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 20D11 |
| 同位型 | IgG1, kappa |
| 靶点名称 | S100A11 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-105 of Human S100A11. |
| 偶联标记 | Un-conjugated |
| 別名 | S100 calcium-binding protein A11; MLN70; MLN 70; Protein S100-C; HEL-S-43; Metastatic lymph node gene 70 protein; Protein S100-A11; S100C; Calgizzarin |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | S100A11 |
| 全名 | S100 calcium binding protein A11 |
| 背景介绍 | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] |
| 生物功能 | Facilitates the differentiation and the cornification of keratinocytes. [UniProt] |
| 预测分子量 | 12 kDa |
| 翻译后修饰 | Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation. |
检测图片 (3) Click the Picture to Zoom In
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ARG57078 anti-S100A11 antibody [20D11] FACS image
Flow Cytometry: A549 cell line stained with ARG57078 anti-S100A11 antibody [20D11] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
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ARG57078 anti-S100A11 antibody [20D11] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) MCF7 cell lysate, 3) PC3 cell lysate, 4) HaCaT cell lysate, 5) THP1 cell lysate, 6) U87MG cell lysate, 7) A427 cell lysate, 8) SK-OV-3 cell lysate, 9) A549 cell lysate stained with ARG57078 anti-S100A11 antibody [20D11] at 1:1000.
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ARG57078 anti-S100A11 antibody [20D11] FACS image
Flow Cytometry: HeLa cell line stained with ARG57078 anti-S100A11 antibody [20D11] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody was Mouse IgG (black line).
