ARG45082
anti-Robo2 antibody
anti-Robo2 antibody for Western blot and Human,Mouse,Rat,Chicken
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Robo2 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Chk |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Robo2 |
| 抗原物种 | Human |
| 抗原 | Robo2 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo2. This sequence has significant homology to the same region in rat and mouse Robo2, and has low homology to other Robo family members. |
| 偶联标记 | Un-conjugated |
| 別名 | ROBO2; Roundabout Guidance Receptor 2; KIAA1568; Roundabout Homolog 2; Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila); Roundabout (Axon Guidance Receptor, Drosophila) Homolog 2; Roundabout, Axon Guidance Receptor, Homolog 2; SAX3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified. |
| 缓冲液 | PBS, 0.05% NaN3, 50% Glycerol and 0.1 % BSA. |
| 稳定剂 | 50% Glycerol and 0.1 % BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ROBO2 |
| 全名 | Roundabout Guidance Receptor 2 |
| 背景介绍 | The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
| 生物功能 | Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. [Uniprot] |
| 细胞定位 | Membrane. [Uniprot] |
| 预测分子量 | 151 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
