ARG45774
anti-Riz1 antibody
anti-Riz1 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Riz1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Riz1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Riz1. |
| 偶联标记 | Un-conjugated |
| 別名 | PRDM2; PR/SET Domain 2; MTB-ZF; KMT8; RIZ; Retinoblastoma Protein-Interacting Zinc Finger Protein; MTE-Binding Protein; HUMHOXY1; KMT8A; RIZ1; RIZ2; Retinoblastoma Protein-Binding Zinc Finger Protein; PR Domain Containing 2, With ZNF Domain; Zinc-Finger DNA-Binding Protein; PR Domain Zinc Finger Protein 2; PR Domain-Containing Protein 2; Lysine N-Methyltransferase 8; GATA-3 Binding Protein G3B; Zinc Finger Protein RIZ; PR Domain 2; GATA-3-Binding Protein G3B; EC 2.1.1.355 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 280 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDM2 |
| 全名 | PR/SET Domain 2 |
| 背景介绍 | This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
| 生物功能 | S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. . [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 189 kDa |
| 翻译后修饰 | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45774 anti-Riz1 antibody IHC-P image
Immunohistochemistry: Human rectum adenocarcinoma stained with ARG45774 anti-Riz1 antibody at 2 μg/ml dilution.
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ARG45774 anti-Riz1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG45774 anti-Riz1 antibody at 5 μg/ml dilution.
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ARG45774 anti-Riz1 antibody IHC-P image
Immunohistochemistry: Mouse testis stained with ARG45774 anti-Riz1 antibody at 2 μg/ml dilution.
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ARG45774 anti-Riz1 antibody WB image
Western blot: K562 stained with ARG45774 anti-Riz1 antibody at 0.5 μg/ml dilution.
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ARG45774 anti-Riz1 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45774 anti-Riz1 antibody at 1 µg/10^6 cells dilution.
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ARG45774 anti-Riz1 antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45774 anti-Riz1 antibody at 2 μg/ml dilution.
