ARG56988
anti-Ribonuclease Inhibitor antibody [1H23]
anti-Ribonuclease Inhibitor antibody [1H23] for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Mouse Monoclonal antibody [1H23] recognizes Ribonuclease Inhibitor |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1H23 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | Ribonuclease Inhibitor |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 7-461 of Human Ribonuclease Inhibitor. |
| 偶联标记 | Un-conjugated |
| 別名 | RNH; Ribonuclease/angiogenin inhibitor 1; RAI; Ribonuclease inhibitor; Placental ribonuclease inhibitor; Placental RNase inhibitor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNH1 |
| 全名 | ribonuclease/angiogenin inhibitor 1 |
| 背景介绍 | Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010] |
| 生物功能 | Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. [UniProt] |
| 预测分子量 | 50 kDa |
| 翻译后修饰 | The N-terminus is blocked. At least 30 of the 32 cysteine residues are in the reduced form. |
检测图片 (2) Click the Picture to Zoom In
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ARG56988 anti-Ribonuclease Inhibitor antibody [1H23] ICC/IF image
Immunoflorescense: PC3 cell line stained with ARG56988 anti-Ribonuclease Inhibitor antibody [1H23] at 1:100 (Green).
DAPI (Blue) for nucleus staining.
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ARG56988 anti-Ribonuclease Inhibitor antibody [1H23] WB image
Western blot: 40 µg of 1) Jurkat cell lysate, 2) HepG2 cell lysate stained with ARG56988 anti-Ribonuclease Inhibitor antibody [1H23] at 1:500.
