ARG41053
anti-Retinoid X Receptor gamma antibody
anti-Retinoid X Receptor gamma antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Retinoid X Receptor gamma |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Retinoid X Receptor gamma |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-137 of Human Retinoid X Receptor gamma (NP_008848.1). |
| 偶联标记 | Un-conjugated |
| 別名 | NR2B3; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma; Retinoic acid receptor RXR-gamma; RXRC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Jurkat | ||||||
| 实际分子量 | 60 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RXRG |
| 全名 | retinoid X receptor, gamma |
| 背景介绍 | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] |
| 生物功能 | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG41053 anti-Retinoid X Receptor gamma antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse testis stained with ARG41053 anti-Retinoid X Receptor gamma antibody at 1:100 dilution.
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ARG41053 anti-Retinoid X Receptor gamma antibody WB image
Western blot: 25 µg of Jurkat cell lysate stained with ARG41053 anti-Retinoid X Receptor gamma antibody at 1:1000 dilution.
