ARG52416
anti-Retinoid X Receptor gamma antibody [1373]
anti-Retinoid X Receptor gamma antibody [1373] for Western blot and Human,Rat
Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [1373] recognizes Retinoid X Receptor gamma |
|---|---|
| 反应物种 | Hu, Rat |
| 预测物种 | Ms, Bov, NHuPrm |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1373 |
| 同位型 | IgG1 |
| 靶点名称 | Retinoid X Receptor gamma |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | NR2B3; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma; Retinoic acid receptor RXR-gamma; RXRC |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | Specific for the ~48k RXR-γ isotype. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RXRG |
| 全名 | retinoid X receptor, gamma |
| 背景介绍 | Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). |
| 研究领域 | Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 51 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG52416 anti-Retinoid X Receptor gamma antibody [1373] WB image
Western Blot: rat hippocampal lysate showing immunolabeling of the ~48k RXR-γ isotype stained with ARG52416 Retinoid X Receptor gamma antibody [1373].
