ARG52415
anti-Retinoid X Receptor beta antibody [147]
anti-Retinoid X Receptor beta antibody [147] for Western blot and Mouse,Rat
Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Mouse Monoclonal antibody [147] recognizes Retinoid X Receptor beta |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 147 |
| 同位型 | IgG1 |
| 靶点名称 | Retinoid X Receptor beta |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide corresponding to amino acid residues from the hinge region conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Retinoic acid receptor RXR-beta; DAUDI6; Retinoid X receptor beta; H-2RIIBP; NR2B2; RCoR-1; Nuclear receptor subfamily 2 group B member 2 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | Specific for the ~48k RXR-β protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Rxrb |
| 全名 | retinoid X receptor beta |
| 背景介绍 | Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). |
| 生物功能 | Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA). Binds to both, class I regulatory element of major histocompatibility class I genes (CRE) and the estrogen response element (ERE). [UniProt] |
| 研究领域 | Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 57 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG52415 anti-Retinoid X Receptor beta antibody [147] WB image
Western blot: Hippocampal lysate showing specific immunolabeling of the ~48 kDa Retinoid X Receptor beta protein stained with ARG52415 anti-Retinoid X Receptor beta antibody [147]
