概述

产品描述	Rabbit Polyclonal antibody recognizes Rad52
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	Rad52
抗原物种	Human
抗原	Synthetic peptide of Human Rad52
偶联标记	Un-conjugated
別名	DNA repair protein RAD52 homolog

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Rat thymus
实际分子量	~ 48 kDa

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 19365 Mouse RAD52 GeneID: 5893 Human RAD52 Swiss-port # P43351 Human DNA repair protein RAD52 homolog Swiss-port # P43352 Mouse DNA repair protein RAD52 homolog
基因名称	RAD52
全名	RAD52 homolog (S. cerevisiae)
背景介绍	The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
生物功能	Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. [UniProt]
预测分子量	46 kDa
翻译后修饰	Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR.

检测图片 (1) Click the Picture to Zoom In