ARG52408
anti-Rabphilin 3A phospho (Ser234) antibody
anti-Rabphilin 3A phospho (Ser234) antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Rat
Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Rabphilin 3A phospho (Ser234) |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Rabphilin 3A |
| 抗原物种 | Rat |
| 抗原 | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH |
| 偶联标记 | Un-conjugated |
| 別名 | Rabphilin-3A; Exophilin-1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | Specific for the ~82k rabphilin protein phosphorylated at Ser234. The immunolabeling of the rabphilin band was completely blocked by the phosphopeptide used as antigen while the dephosphopeptide had no effect on the immunolabeling * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| 稳定剂 | 0.1 mg/ml BSA, 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RPH3A |
| 全名 | rabphilin 3A |
| 背景介绍 | Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994;Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington’s disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995;Foletti and Scheller, 2001). |
| 研究领域 | Neuroscience antibody |
| 预测分子量 | 77 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody WB image
Western blot: Rat brain lysate showing specific immunolabeling of the ~82k rabphilin 3A phosphorylated at Ser 234 stained with ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody.
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ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody IHC image
Immunohistochemistry: 14 DIV Rat cortical neurons showing Rabphilin 3A when phosphorylated at Ser234 stained with ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody in red and PSD95 in green.
