ARG45955
anti-RYK antibody
anti-RYK antibody for Flow cytometry,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RYK |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RYK |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human RYK. |
| 偶联标记 | Un-conjugated |
| 別名 | Receptor Like Tyrosine Kinase; RYK; JTK5A; Tyrosine-protein kinase RYK; EC 2.7.10.1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 75 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RYK |
| 全名 | Receptor Like Tyrosine Kinase |
| 背景介绍 | The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. [provided by RefSeq, Jul 2008] |
| 生物功能 | May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. [UniProt] |
| 细胞定位 | Nucleus; Cytoplasm; Membrane. [UniProt] |
| 预测分子量 | 68 kDa |
| 翻译后修饰 | Phosphoprotein; Disulfide bond; Glycoprotein. [UniProt]. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45955 anti-RYK antibody WB image
Western blot: MCF-7 stained with ARG45955 anti-RYK antibody at 0.5 μg/ml dilution.
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ARG45955 anti-RYK antibody FACS image
Flow Cytometry: MCF-7 stained with ARG45955 anti-RYK antibody at 1 µg/10^6 cells dilution.
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ARG45955 anti-RYK antibody WB image
Western blot: Rat ovary stained with ARG45955 anti-RYK antibody at 0.5 μg/ml dilution.
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ARG45955 anti-RYK antibody WB image
Western blot: Mouse ovary stained with ARG45955 anti-RYK antibody at 0.5 μg/ml dilution.
