ARG46449
anti-RUSC1 antibody
anti-RUSC1 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RUSC1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RUSC1 |
| 抗原物种 | Human |
| 抗原 | A 17 amino acid synthetic peptide within the last 50 amino acids of human RUSC1. |
| 偶联标记 | Un-conjugated |
| 別名 | RUN and SH3 domain containing 1; RUSC1; NESCA; NESCA; RUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -499°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8BG26 Mouse RUN and SH3 domain-containing protein 1 Swiss-port # Q9BVN2 Human RUN and SH3 domain-containing protein 1 |
|---|---|
| 基因名称 | RUSC1 |
| 全名 | RUN and SH3 domain containing 1 |
| 背景介绍 | Predicted to enable actin binding activity. Involved in protein polyubiquitination. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025] |
| 生物功能 | Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network (PubMed:30262884). Signaling adapter which plays a role in neuronal differentiation (PubMed:15024033). Involved in regulation of NGF-dependent neurite outgrowth (PubMed:15024033). May play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins (By similarity). Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK (PubMed:15024033). Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway (PubMed:19365808). [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus; Endosome; Cytoplasmic vesicle; Cytoplasmic vesicle; Golgi apparatus. [UniProt] |
| 预测分子量 | 96 kDa |
| 翻译后修饰 | Phosphoprotein; Ubl conjugation. [UniProt] |
