ARG45312
anti-RUFY4 antibody
anti-RUFY4 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Monkey
概述
| 产品描述 | Polyclonal antibody recognizes RUFY4 |
|---|---|
| 反应物种 | Hu, Mk |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RUFY4 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human RUFY4. |
| 偶联标记 | Un-conjugated |
| 別名 | RUFY4; RUN And FYVE Domain Containing 4; ZFYVE31; RUN And FYVE Domain-Containing Protein 4; FLJ46536 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 64 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6ZNE9 Human RUN and FYVE domain-containing protein 4 |
|---|---|
| 基因名称 | RUFY4 |
| 全名 | RUN And FYVE Domain Containing 4 |
| 背景介绍 | Enables phosphatidylinositol-3-phosphate binding activity. Involved in autophagosome assembly; cellular response to interleukin-4; and positive regulation of macroautophagy. Located in autophagosome. [provided by Alliance of Genome Resources, Nov 2024] |
| 生物功能 | Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger. [UniProt] |
| 细胞定位 | Cytoplasmic vesicle. [UniProt] |
| 预测分子量 | 64 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG45312 anti-RUFY4 antibody IHC-P image
Immunohistochemistry: Human tonsil stained with ARG45312 anti-RUFY4 antibody at 2 μg/ml dilution.
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ARG45312 anti-RUFY4 antibody WB image
Western blot: Human placenta stained with ARG45312 anti-RUFY4 antibody at 0.5 μg/ml dilution.
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ARG45312 anti-RUFY4 antibody FACS image
Flow Cytometry: HEL stained with ARG45312 anti-RUFY4 antibody at 1 µg/10^6 cells dilution.
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ARG45312 anti-RUFY4 antibody WB image
Western blot: COS-7 stained with ARG45312 anti-RUFY4 antibody at 0.5 μg/ml dilution.
