概述

产品描述	Rabbit Polyclonal antibody recognizes RUFY1
反应物种	Hu
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	RUFY1
抗原物种	Human
抗原	Synthetic peptide within aa. 110-190 of Human RUFY1.
偶联标记	Un-conjugated
別名	FYVE-finger protein EIP1; RUN and FYVE domain-containing protein 1; ZFYVE12; Zinc finger FYVE domain-containing protein 12; Rab4-interacting protein; La-binding protein 1; RABIP4

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	~ 80 kDa

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol and 0.5% BSA
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 80230 Human RUFY1 Swiss-port # Q96T51 Human RUN and FYVE domain-containing protein 1
基因名称	RUFY1
全名	RUN and FYVE domain containing 1
背景介绍	This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
生物功能	Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. [UniProt]
细胞定位	Cytoplasm. Early endosome membrane; Peripheral membrane protein. [UniProt]
预测分子量	80 kDa
翻译后修饰	Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting. [UniProt]

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