ARG44076
anti-RUFY1 antibody
anti-RUFY1 antibody for Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal recognizes RUFY1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RUFY1 |
| 抗原物种 | Human |
| 抗原 | Human RUFY1 recombinant protein (Position: L20-Q650). |
| 偶联标记 | Un-conjugated |
| 別名 | FYVE-finger protein EIP1; RUN and FYVE domain-containing protein 1; ZFYVE12; Zinc finger FYVE domain-containing protein 12; Rab4-interacting protein; La-binding protein 1; RABIP4 |
应用说明
| 应用建议 |
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| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96T51 Human RUN and FYVE domain-containing protein 1 |
|---|---|
| 基因名称 | RUFY1 |
| 全名 | RUN and FYVE domain containing 1 |
| 背景介绍 | This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. [UniProt] |
| 细胞定位 | Cytoplasm. Early endosome membrane; Peripheral membrane protein. [UniProt] |
| 预测分子量 | 80 kDa |
| 翻译后修饰 | Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG44076 anti-RUFY1 antibody WB image
Western blot: HeLa and SiHa stained with ARG44076 anti-RUFY1 antibody at 0.5 μg/mL dilution.
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ARG44076 anti-RUFY1 antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44076 anti-RUFY1 antibody at 1 µg/10^6 cells dilution.
