ARG44018
anti-RTN4 / Nogo A antibody
anti-RTN4 / Nogo A antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RTN4 / Nogo A |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RTN4 / Nogo A |
| 抗原物种 | Human |
| 抗原 | Human RTN4 / Nogo A recombinantprotein |
| 偶联标记 | Un-conjugated |
| Protein Full name | Reticulon-4 |
| 別名 | RTN4; Reticulon 4; NOGO; KIAA0886; NSP-CL; ASY; Neuroendocrine-Specific Protein C Homolog; Neurite Outgrowth Inhibitor; Reticulon-4; Foocen; RTN-X; NSP; Neuroendocrine-Specific Protein; Neurite Growth Inhibitor 220; My043 Protein; Nogo Protein; Human NogoA; Reticulon 5; Reticulon-5; NI220/250; Nbla00271; Nbla10545; RTN4-B1; RTN4-B2; RTN4-A; RTN4-C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS containing 0.02% sodium azide |
| 抗菌剂 | 0.02% sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RTN4 |
| 全名 | Reticulon 4 |
| 背景介绍 | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. |
| 生物功能 | Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. |
| 细胞定位 | Cell junction, Cell membrane, Endoplasmic reticulum, Membrane |
| 预测分子量 | 130 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (2) Click the Picture to Zoom In
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ARG44018 anti-RTN4 / Nogo A antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44018 anti-RTN4 / Nogo A antibody at 20 μg/mL dilution.
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ARG44018 anti-RTN4 / Nogo A antibody WB image
Western blot: Human brain stained with ARG44018 anti-RTN4 / Nogo A antibody at 1 μg/mL dilution.
