ARG57574
anti-RRAS2 / TC21 antibody [EM-50]
anti-RRAS2 / TC21 antibody [EM-50] for Flow cytometry,ICC/IF and Human
概述
| 产品描述 | Mouse Monoclonal antibody [EM-50] recognizes RRAS2 / TC21 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF |
| 特异性 | The antibody recognizes RRAS2 / TC21 protein and does not react with RRAS1, H-Ras, K-Ras, and N-Ras. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | EM-50 |
| 同位型 | IgG1 |
| 靶点名称 | RRAS2 / TC21 |
| 抗原物种 | Human |
| 抗原 | Human TC21. |
| 偶联标记 | Un-conjugated |
| 別名 | TC21; Teratocarcinoma oncogene; Ras-related protein R-Ras2; Ras-like protein TC21 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide. |
| 抗菌剂 | 15mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RRAS2 |
| 全名 | RRAS2 |
| 背景介绍 | This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] |
| 生物功能 | It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. [UniProt] |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | May be post-translationally modified by both palmitoylation and polyisoprenylation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
-
ARG57574 anti-RRAS2 / TC21 antibody [EM-50] ICC/IF image
Immunofluorescence: Colocalization of RRAS2 / TC21 signal (red) and GFP signal (green) in COS cells transfected with RRAS2 / TC21-GFP construct, after fixation and permeabilization. RRAS2 / TC21 was detected using ARG57574 anti-RRAS2 / TC21 antibody [EM-50].
-
ARG57574 anti-RRAS2 / TC21 antibody [EM-50] FACS image
Flow Cytometry: RRAS2-GFP transfected HEK293 cells stained with ARG57574 anti-RRAS2 / TC21 antibody [EM-50], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.
