ARG42669
anti-RRAS2 / TC21 antibody
anti-RRAS2 / TC21 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RRAS2 / TC21 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RRAS2 / TC21 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-204 of Human RRAS2 / TC21 (NP_036382.2). |
| 偶联标记 | Un-conjugated |
| 別名 | TC21; Teratocarcinoma oncogene; Ras-related protein R-Ras2; Ras-like protein TC21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HT-29 and NIH/3T3 | ||||
| 实际分子量 | 23 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RRAS2 |
| 全名 | related RAS viral (r-ras) oncogene homolog 2 |
| 背景介绍 | This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] |
| 生物功能 | It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. [UniProt] |
| 细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS). [UniProt] |
| 预测分子量 | ~ 23 kDa |
| 翻译后修饰 | May be post-translationally modified by both palmitoylation and polyisoprenylation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG42669 anti-RRAS2 / TC21 antibody WB image
Western blot: 25 µg of HT-29 cell lysate stained with ARG42669 anti-RRAS2 / TC21 antibody at 1:1000 dilution.
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ARG42669 anti-RRAS2 / TC21 antibody WB image
Western blot: 25 µg of NIH/3T3 cell lysate stained with ARG42669 anti-RRAS2 / TC21 antibody at 1:1000 dilution.
