ARG58278
anti-ROR2 antibody
anti-ROR2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes ROR2 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | ROR2 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 756-790 (C-terminus) of Human ROR2. |
| 偶联标记 | Un-conjugated |
| 別名 | BDB; Neurotrophic tyrosine kinase, receptor-related 2; NTRKR2; BDB1; Tyrosine-protein kinase transmembrane receptor ROR2; EC 2.7.10.1 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa | ||||||
| 实际分子量 | 120 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q01974 Human Tyrosine-protein kinase transmembrane receptor ROR2 |
|---|---|
| 基因名称 | ROR2 |
| 全名 | receptor tyrosine kinase-like orphan receptor 2 |
| 背景介绍 | The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008] |
| 生物功能 | Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 105 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG58278 anti-ROR2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse stomach tissue stained with ARG58278 anti-ROR2 antibody at 1:25 dilution.
-
ARG58278 anti-ROR2 antibody WB image
Western blot: 20 µg of HeLa cell lysate stained with ARG58278 anti-ROR2 antibody at 1:1000 dilution.
