ARG45306
anti-RNase H1 / RNH1 antibody
anti-RNase H1 / RNH1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Polyclonal antibody recognizes RNase H1 / RNH1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RNase H1 / RNH1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human RNase H1 / RNH1. |
| 偶联标记 | Un-conjugated |
| 別名 | RNASEH1; Ribonuclease H1; Ribonuclease H Type II; RNase H1; RNH1; EC 3.1.26.4; H1RNA; PEOB2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 38 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNASEH1 |
| 全名 | Ribonuclease H1 |
| 背景介绍 | This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017] |
| 生物功能 | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 32 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG45306 anti-RNase H1 / RNH1 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45306 anti-RNase H1 / RNH1 antibody at 5 ug/ml dilution.
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ARG45306 anti-RNase H1 / RNH1 antibody WB image
Western blot: Hela and SH-SY5Y stained with ARG45306 anti-RNase H1 / RNH1 antibody at 0.5 μg/ml dilution.
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ARG45306 anti-RNase H1 / RNH1 antibody FACS image
Flow Cytometry: HepG2 stained with ARG45306 anti-RNase H1 / RNH1 antibody at 1 µg/10^6 cells dilution.
