ARG41588
anti-RNF220 antibody
anti-RNF220 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RNF220 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RNF220 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 267-566 of Human RNF220 (NP_060620.2). |
| 偶联标记 | Un-conjugated |
| 別名 | RING finger protein 220; E3 ubiquitin-protein ligase RNF220; EC 6.3.2.-; C1orf164 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse brain | ||||
| 实际分子量 | ~ 72 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5VTB9 Human E3 ubiquitin-protein ligase RNF220 Swiss-port # Q6PDX6 Mouse E3 ubiquitin-protein ligase Rnf220 |
|---|---|
| 基因名称 | RNF220 |
| 全名 | ring finger protein 220 |
| 生物功能 | E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 63 kDa |
| 翻译后修饰 | Auto-ubiquitinated; leads to proteasomal degradation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41588 anti-RNF220 antibody WB image
Western blot: 25 µg of Mouse brain lysate stained with ARG41588 anti-RNF220 antibody at 1:1000 dilution.
