ARG44919
anti-RNF146 antibody
anti-RNF146 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Human,Rat
概述
| 产品描述 | Mouse Monoclonal antibody recognizes RNF146 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | IHC-P, IP |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | RNF146 |
| 抗原物种 | Human |
| 抗原表位 | NLARESSADG ADSVSAQSGA SVQPLVSSVR PLTSVDGQLT SPATPSPDAS TSLEDSFAHL QLSGDNTAER SHRGEGEEDH ESPSSGRVPA PDTSIEETES DASSDSEDVS AVVAQHSLTQ QRLLVSNANQ |
| 偶联标记 | Un-conjugated |
| 別名 | RNF146; Ring Finger Protein 146; Dactylidin; RING-Type E3 Ubiquitin Transferase RNF146; E3 Ubiquitin-Protein Ligase RNF146; DKFZp434O1427; DJ351K20.1; Iduna; RING Finger Protein 146; EC 2.3.2.27 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q5XIK5 Rat E3 ubiquitin-protein ligase RNF146 Swiss-port # Q9NTX7 Human E3 ubiquitin-protein ligase RNF146 |
|---|---|
| 基因名称 | RNF146 |
| 全名 | Ring Finger Protein 146 |
| 背景介绍 | Enables poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Involved in positive regulation of canonical Wnt signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Promotes cell survival after gamma-irradiation. Facilitates DNA repair. [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus. [UniProt] |
| 预测分子量 | 39 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG44919 anti-RNF146 antibody IHC-P image
Immunohistochemistry: Human gall bladder stained with ARG44919 anti-RNF146 antibody at 10 µg/mL dilution.
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ARG44919 anti-RNF146 antibody IP image
Immunoprecipitation: Rat brain lysate immunoprecipitated with 2.5 µg of ARG44919 anti-RNF146 antibody.
