ARG40066
anti-RNASEH2C / RNase H2 subunit C antibody
anti-RNASEH2C / RNase H2 subunit C antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RNASEH2C / RNase H2 subunit C |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RNASEH2C / RNase H2 subunit C |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-164 of Human RNASEH2C (NP_115569.2). |
| 偶联标记 | Un-conjugated |
| 別名 | RNase H1 small subunit; Ribonuclease H2 subunit C; Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H2 subunit C; AYP1; Ribonuclease HI subunit C |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | 293T | ||||
| 实际分子量 | 18 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNASEH2C |
| 全名 | ribonuclease H2, subunit C |
| 背景介绍 | This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 18 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40066 anti-RNASEH2C / RNase H2 subunit C antibody WB image
Western blot: 25 µg of 293T cell lysate stained with ARG40066 anti-RNASEH2C / RNase H2 subunit C antibody at 1:1000 dilution.
