ARG59108
anti-RNASE1 / Ribonuclease A antibody
anti-RNASE1 / Ribonuclease A antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RNASE1 / Ribonuclease A |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RNASE1 / Ribonuclease A |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 72-90 of Human RNASE1 / Ribonuclease A. (NTFVHEPLVDVQNVCFQEK) |
| 偶联标记 | Un-conjugated |
| 別名 | Ribonuclease A; RNase A; RNS1; RAC1; RIB1; EC 3.1.27.5; Ribonuclease 1; RNase 1; Ribonuclease pancreatic; RNase UpI-1; RIB-1; HP-RNase |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNASE1 |
| 全名 | ribonuclease, RNase A family, 1 (pancreatic) |
| 背景介绍 | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 18 kDa |
| 翻译后修饰 | N-linked glycans are of complex type. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59108 anti-RNASE1 / Ribonuclease A antibody WB image
Western blot: 40 µg of MCF-7, U87, HeLa, MDA-MB-231, Jurkat, SMMC-7721, COLO320, SW620 and CEM cell lysates stained with ARG59108 anti-RNASE1 / Ribonuclease A antibody at 0.5 µg/ml dilution.
