ARG45599
anti-RGS3 antibody
anti-RGS3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RGS3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RGS3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of mouse RGS3. |
| 偶联标记 | Un-conjugated |
| 別名 | RGS3; Regulator Of G Protein Signaling 3; Regulator Of G-Protein Signaling 3; C2PA; Regulator Of G-Protein Signalling 3; FLJ20370; PDZ-RGS3; RGP3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RGS3 |
| 全名 | Regulator Of G Protein Signaling 3 |
| 背景介绍 | This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTPase-activating protein that inhibits G-protein-mediated signal transduction. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. Long isoforms are largely cytosolic and plasma membrane-associated with a function in Wnt signaling and in the epithelial mesenchymal transition, while shorter N-terminally-truncated isoforms can be nuclear. [provided by RefSeq, Jan 2013] |
| 生物功能 | Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases. [UniProt] |
| 细胞定位 | Cell membrane; Cytoplasm; Membrane; Nucleus. [UniProt] |
| 预测分子量 | 132 kDa |
| 翻译后修饰 | Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (3) Click the Picture to Zoom In
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ARG45599 anti-RGS3 antibody IHC-P image
Immunohistochemistry: Rat intestine stained with ARG45599 anti-RGS3 antibody at 2 μg/ml dilution.
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ARG45599 anti-RGS3 antibody WB image
Western blot: Hela stained with ARG45599 anti-RGS3 antibody.
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ARG45599 anti-RGS3 antibody WB image
Western blot: Rat testis stained with ARG45599 anti-RGS3 antibody.
