ARG63582

anti-RGS18 antibody

anti-RGS18 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Signaling Transduction antibody

概述

产品描述 Goat Polyclonal antibody recognizes RGS18
反应物种 Hu
应用 IHC-P, WB
宿主 Goat
克隆 Polyclonal
同位型 IgG
靶点名称 RGS18
抗原物种 Human
抗原 CNEFQDVQSDVAIWL
偶联标记 Un-conjugated
別名 Regulator of G-protein signaling 18; RGS13; RGS18

应用说明

应用建议
应用 推荐稀释比
IHC-P5 µg/ml
WB1 - 3 µg/ml
应用说明 WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purified from goat serum by antigen affinity chromatography.
缓冲液 Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 0.5% BSA
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 64407 Human RGS18

Swiss-port # Q9NS28 Human Regulator of G-protein signaling 18

背景介绍 This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
研究领域 Signaling Transduction antibody
预测分子量 28 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG63582 anti-RGS18 antibody WB image

    Western Blot: Human Peripheral Blood Mononucleocytes lysate (35 µg protein in RIPA buffer) stained with ARG63582 anti-RGS18 antibody at 1 µg/ml dilution.

  • ARG63582 anti-RGS18 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63582 anti-RGS18 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63582 anti-RGS18 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63582 anti-RGS18 antibody at 5 µg/ml dilution followed by AP-staining.