ARG45294
anti-RFX3 antibody
anti-RFX3 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Polyclonal antibody recognizes RFX3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RFX3 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human RFX3. |
| 偶联标记 | Un-conjugated |
| 別名 | RFX3; Regulatory Factor X3; Regulatory Factor X, 3 (Influences HLA Class II Expression); Transcription Factor RFX3; DNA Binding Protein RFX3; Regulatory Factor X 3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 95 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RFX3 |
| 全名 | Regulatory Factor X3 |
| 背景介绍 | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013] |
| 生物功能 | Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development. Essential for the differentiation of nodal monocilia and left-right asymmetry specification during embryogenesis. Required for the biogenesis of motile cilia by governing growth and beating efficiency of motile cells. Also required for ciliated ependymal cell differentiation. Regulates the expression of genes involved in ciliary assembly (DYNC2LI1, FOXJ1 and BBS4) and genes involved in ciliary motility (DNAH11, DNAH9 and DNAH5). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 84 kDa |
检测图片 (5) Click the Picture to Zoom In
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ARG45294 anti-RFX3 antibody ICC/IF image
Immunofluorescence: U20S stained with ARG45294 anti-RFX3 antibody at 5 ug/ml dilution.
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ARG45294 anti-RFX3 antibody WB image
Western blot: HEL and SH-SY5Y stained with ARG45294 anti-RFX3 antibody at 0.5 μg/ml dilution.
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ARG45294 anti-RFX3 antibody FACS image
Flow Cytometry: RT4 stained with ARG45294 anti-RFX3 antibody at 1 µg/10^6 cells dilution.
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ARG45294 anti-RFX3 antibody IHC-P image
Immunohistochemistry: Rat brain stained with ARG45294 anti-RFX3 antibody at 2 μg/ml dilution.
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ARG45294 anti-RFX3 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG45294 anti-RFX3 antibody at 2 μg/ml dilution.
