概述

产品描述	Rabbit Polyclonal antibody recognizes RERE
反应物种	Hu, Ms, Rat
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	RERE
抗原物种	Human
抗原	Recombinant fusion protein corresponding to aa. 1-220 of Human RERE (NP_036234.3).
偶联标记	Un-conjugated
別名	ARP; Arginine-glutamic acid dipeptide repeats protein; Atrophin-1-related protein; Atrophin-1-like protein; ARG; ATN1L; DNB1

应用说明

应用建议	应用 推荐稀释比 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照	Jurkat
实际分子量	172 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 116665 Rat RERE GeneID: 473 Human RERE GeneID: 68703 Mouse RERE Swiss-port # Q62901 Rat Arginine-glutamic acid dipeptide repeats protein Swiss-port # Q80TZ9 Mouse Arginine-glutamic acid dipeptide repeats protein Swiss-port # Q9P2R6 Human Arginine-glutamic acid dipeptide repeats protein More
基因名称	RERE
全名	arginine-glutamic acid dipeptide (RE) repeats
背景介绍	This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. [UniProt]
细胞定位	Nucleus. [UniProt]
预测分子量	172 kDa

检测图片 (1) Click the Picture to Zoom In