ARG40822
anti-REG3A antibody
anti-REG3A antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes REG3A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 特异性 | This antibody might also react to REG3G based on sequence analysis. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | REG3A |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 27-175 of Human REG3A (NP_002571.1). |
| 偶联标记 | Un-conjugated |
| 別名 | HIP; PAP; HIP/PAP; Regenerating islet-derived protein 3-alpha; PAP-H; REG-III; Hepatointestinal pancreatic protein; PBCGF; Human proislet peptide; REG3; INGAP; Regenerating islet-derived protein III-alpha; REG-3-alpha; Reg III-alpha; PAP1; Pancreatitis-associated protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse pancreas | ||||||
| 实际分子量 | 14.5 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | REG3A |
| 全名 | regenerating islet-derived 3 alpha |
| 背景介绍 | This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014] |
| 生物功能 | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. [UniProt] |
| 细胞定位 | Secreted. Note=Found in the apical region of pancreatic acinar cells. [UniProt] |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40822 anti-REG3A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG40822 anti-REG3A antibody.
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ARG40822 anti-REG3A antibody WB image
Western blot: 25 µg of Mouse pancreas lysate stained with ARG40822 anti-REG3A antibody at 1:1000 dilution.
