ARG40787
anti-REG3A antibody
anti-REG3A antibody for Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes REG3A |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | REG3A |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 129-163 of Human REG3A. |
| 偶联标记 | Un-conjugated |
| 別名 | HIP; PAP; HIP/PAP; Regenerating islet-derived protein 3-alpha; PAP-H; REG-III; Hepatointestinal pancreatic protein; PBCGF; Human proislet peptide; REG3; INGAP; Regenerating islet-derived protein III-alpha; REG-3-alpha; Reg III-alpha; PAP1; Pancreatitis-associated protein 1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q06141 Human Regenerating islet-derived protein 3-alpha |
|---|---|
| 基因名称 | REG3A |
| 全名 | regenerating islet-derived 3 alpha |
| 背景介绍 | This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014] |
| 生物功能 | Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. [UniProt] |
| 细胞定位 | Secreted. Note=Found in the apical region of pancreatic acinar cells. [UniProt] |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG40787 anti-REG3A antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG40787 anti-REG3A antibody at 1:25 dilution (right histogram) or isotype control antibody (left histogram), followed by incubation with Alexa Fluor® 488 labelled secondary antibody.
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ARG40787 anti-REG3A antibody WB image
Western blot: 35 µg of Human pancreas lysate stained with ARG40787 anti-REG3A antibody at 1:1000 dilution.
