ARG59910
anti-RBM17 antibody
anti-RBM17 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RBM17 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RBM17 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-240 of Human RBM17 (NP_116294.1). |
| 偶联标记 | Un-conjugated |
| 別名 | 45 kDa-splicing factor; SPF45; RNA-binding motif protein 17; Splicing factor 45 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Rat thymus and DU145 | ||||||
| 实际分子量 | 50 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RBM17 |
| 全名 | RNA binding motif protein 17 |
| 背景介绍 | This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009] |
| 生物功能 | Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 45 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG59910 anti-RBM17 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse lung stained with ARG59910 anti-RBM17 antibody at 1:100 dilution.
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ARG59910 anti-RBM17 antibody WB image
Western blot: 25 µg of Rat thymus and DU145 cell lysates stained with ARG59910 anti-RBM17 antibody at 1:1000 dilution.
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ARG59910 anti-RBM17 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain stained with ARG59910 anti-RBM17 antibody at 1:100 dilution.
