ARG11142
anti-RBFOX2 / RBM9 antibody
anti-RBFOX2 / RBM9 antibody for IHC-Frozen sections and Human,Mouse,Rat
概述
| 产品描述 | Chicken Polyclonal antibody recognizes RBFOX2 / RBM9 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-Fr |
| 宿主 | Chicken |
| 克隆 | Polyclonal |
| 同位型 | IgY |
| 靶点名称 | RBFOX2 / RBM9 |
| 抗原物种 | Human |
| 抗原 | The N-terminal 99 amino acids of Human RBFOX2 / RBM9. |
| 偶联标记 | Un-conjugated |
| 別名 | RNA binding protein fox-1 homolog 2; dJ106I20.3; RTA; HRNBP2; HNRBP2; Fox-1 homolog B; RBM9; Hexaribonucleotide-binding protein 2; RNA-binding protein 9; fxh; Repressor of tamoxifen transcriptional activity; Fox-2; FOX2; RNA-binding motif protein 9 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 5 mM Sodium azide. |
| 抗菌剂 | 5 mM Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RBFOX2 |
| 全名 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| 背景介绍 | This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. [UniProt] |
| 预测分子量 | 41 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG11142 anti-RBFOX2 / RBM9 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Mouse cerebellum tissue stained with ARG11142 anti-RBFOX2 / RBM9 antibody (red) at 1:2000 dilution, and co-stained with anti-Neurofilament NF-L antibody (green) at 1:5000 dilution. Hoechst (blue) for nuclear staining. (Sample preparation: Following transcardial perfusion of mouse with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 µM, and free-floating sections were stained with above antibodies.).
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ARG11142 anti-RBFOX2 / RBM9 antibody IHC-Fr image
Immunohistochemistry: Frozen section of Rat hippocampus tissue stained with ARG11142 anti-RBFOX2 / RBM9 antibody (red) at 1:2000 dilution, and co-stained with ARG10720 anti-MAP2cd antibody [2C4] (green) at 1:5000 dilution. Hoechst (blue) for nuclear staining. (Sample preparation: Following transcardial perfusion of rat with 4% paraformaldehyde, brain was post fixed for 24 hours, cut to 45 µM, and free-floating sections were stained with above antibodies.).
