ARG64433
anti-RASSF7 / HRAS1 antibody
anti-RASSF7 / HRAS1 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes RASSF7 / HRAS1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RASSF7 / HRAS1 |
| 抗原物种 | Human |
| 抗原 | CTDLRGLELRVQRN |
| 偶联标记 | Un-conjugated |
| 別名 | HRAS1-related cluster protein 1; HRC1; C11orf13; HRAS1; Ras association domain-containing protein 7 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q02833 Human Ras association domain-containing protein 7 |
|---|---|
| 基因名称 | RASSF7 |
| 全名 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 |
| 生物功能 | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Gene Regulation antibody |
| 预测分子量 | 40 kDa |
| 翻译后修饰 | Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli. |
检测图片 (1) Click the Picture to Zoom In
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ARG64433 anti-RASSF7 / HRAS1 antibody WB image
Western Blot: Jurkat cell lysate (35 µg protein in RIPA buffer) stained with ARG64433 anti-RASSF7 / HRAS1 antibody at 1 µg/ml dilution.
