ARG42860
anti-RASSF2 antibody
anti-RASSF2 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RASSF2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RASSF2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human RASSF2. |
| 偶联标记 | Un-conjugated |
| 別名 | CENP-34; Ras association domain-containing protein 2; RASFADIN |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa | ||||
| 实际分子量 | ~ 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P50749 Human Ras association domain-containing protein 2 |
|---|---|
| 基因名称 | RASSF2 |
| 全名 | Ras association (RalGDS/AF-6) domain family member 2 |
| 背景介绍 | This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008] |
| 生物功能 | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. [UniProt] |
| 细胞定位 | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1. [UniProt] |
| 预测分子量 | 38 kDa |
| 翻译后修饰 | Phosphorylated by STK3/MST2 and STK4/MST1. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG42860 anti-RASSF2 antibody WB image
Western blot: HeLa cell lysate stained with ARG42860 anti-RASSF2 antibody at 1:1000 dilution.
