ARG63366
anti-RANBP8 / IPO8 antibody
anti-RANBP8 / IPO8 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Gene Regulation antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes RANBP8 / IPO8 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Cow, Dog, Pig |
| 应用 | IHC-P |
| 特异性 | This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1). |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RANBP8 / IPO8 |
| 抗原物种 | Human |
| 抗原 | C-SAFNFGTVPSNN |
| 偶联标记 | Un-conjugated |
| 別名 | Imp8; Importin-8; Ran-binding protein 8; RANBP8; RanBP8 |
应用说明
| 应用建议 |
|
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| 研究领域 | Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 120 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG63366 anti-RANBP8 / IPO8 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Tonsil. (Steamed antigen retrieval with Tris/EDTA buffer pH 9) stained with ARG63366 anti-RANBP8 / IPO8 antibody at 4 µg/ml dilution followed by HRP-staining. Similar results were obtained after antigen retrieval at pH9.
