ARG64599
anti-RAMP1 antibody
anti-RAMP1 antibody for Western blot and Rat
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Goat Polyclonal antibody recognizes RAMP1 |
|---|---|
| 反应物种 | Rat |
| 预测物种 | Hu, Ms |
| 应用 | WB |
| 特异性 | This antibody is expected to recognize isoform 1 (NP_058590.1) only. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RAMP1 |
| 抗原物种 | Mouse |
| 抗原 | C-DYQSKRTEGIV |
| 偶联标记 | Un-conjugated |
| 別名 | CRLR activity-modifying protein 1; Calcitonin-receptor-like receptor activity-modifying protein 1; Receptor activity-modifying protein 1 |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by antigen affinity chromatography. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9JJ74 Rat Receptor activity-modifying protein 1 |
|---|---|
| 基因名称 | Ramp1 |
| 全名 | receptor (calcitonin) activity modifying protein 1 |
| 背景介绍 | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. [provided by RefSeq, Jul 2008] |
| 生物功能 | Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. [UniProt] |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 17 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG64599 anti-RAMP1 antibody WB image
Western blot: Rat Brain lysate (35 µg protein in RIPA buffer) stained with ARG64599 anti-RAMP1 antibody at 0.3 µg/ml dilution.
