ARG45520
anti-RALB antibody
anti-RALB antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RALB |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RALB |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to C-terminal region of human RALB. |
| 偶联标记 | Un-conjugated |
| 別名 | RALB; v-ral simian leukemia viral oncogene homolog B; Ras-related protein Ral-B |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 23 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RALB |
| 全名 | v-ral simian leukemia viral oncogene homolog B |
| 背景介绍 | This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. [provided by RefSeq, Jul 2008] |
| 生物功能 | Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis. [UniProt] |
| 细胞定位 | Cell membrane. [UniProt] |
| 预测分子量 | 23 kDa |
| 翻译后修饰 | Prenylation is essential for membrane localization. The geranylgeranylated form and the farnesylated mutant does not undergo alternative prenylation in response to geranylgeranyltransferase I inhibitors (GGTIs) and farnesyltransferase I inhibitors (FTIs). The farnesylated form confers resistance to the proapoptotic and anti-anchorage-dependent growth effects of geranylgeranyltransferase I inhibitors, including GGTI-2417.. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
-
ARG45520 anti-RALB antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45520 anti-RALB antibody at 5 μg/ml dilution.
-
ARG45520 anti-RALB antibody WB image
Western blot: Hela stained with ARG45520 anti-RALB antibody at 0.5 μg/ml dilution.
-
ARG45520 anti-RALB antibody FACS image
Flow Cytometry: Jurkat stained with ARG45520 anti-RALB antibody at 1 µg/10^6 cells dilution.
-
ARG45520 anti-RALB antibody WB image
Western blot: Rat Brain stained with ARG45520 anti-RALB antibody at 0.5 μg/ml dilution.
-
ARG45520 anti-RALB antibody WB image
Western blot: Mouse Spleen stained with ARG45520 anti-RALB antibody at 0.5 μg/ml dilution.
