概述

产品描述	Rabbit Polyclonal antibody recognizes RAET1E / ULBP4
反应物种	Hu, Ms
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	RAET1E / ULBP4
抗原物种	Human
抗原	A 18 amino acid synthetic peptide within the last 50 amino acids of human RAET1E / ULBP4.
偶联标记	Un-conjugated
別名	RAET1E; LETAL; Retinoic acid early transcript 1E; RAE-1-like transcript 4; bA350J20.7; N2DL-4; NKG2DL4; ULBP4; RAET1E2; RL-4; Lymphocyte effector toxicity activation ligand; NKG2D ligand 4

应用说明

应用建议	应用 推荐稀释比 WB Assay-dependent
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	29 kDa

属性

纯化	Affinity chromatography purified
缓冲液	PBS and 0.02% Sodium azide.
抗菌剂	0.02% Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 135250 Human RAET1E GeneID: 379043 Mouse RAET1E Swiss-port # Q8TD07 Human NKG2D ligand 4 Swiss-port # Q9CZQ6 Mouse Retinoic acid early-inducible protein 1-epsilon
基因名称	RAET1E
全名	retinoic acid early transcript 1E
背景介绍	This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
生物功能	Ligand for the KLRK1 receptor. Delivers activating signals to NK cells and promotes tumor immune surveillance by inducing the expansion of anti-tumor cytotoxic lymphocytes. [UniProt]
预测分子量	29 kDa

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